ASSOCIATION OF BLOOD LIPID AND GLUCOSE LEVELS WITH CAROTID INTIMA MEDIA THICKNESS

Main Article Content

Syed Aown Raza Bokhari
Sikandar Hayat Khan
Muhammad Shahzad Hanif
Mariam Hassan
Naila Azam

Abstract

Objective: To measure the differences in CIMT across groups based upon normal and higher levels offasting glucose and lipids.

Methodology: This cross sectional study was carried out between January to June 2011 at department ofradiology and pathology, PNS Rahat hospital Karachi. From a target population of patients presenting forfasting blood glucose measurement, a total 0f 201 subjects were shortlisted and consented after variousexclusion. These patients were sampled for glucose and lipids after brief clinical evaluation. Later subjectsunderwent CIMT measurement in radiology department.

Results: Age showed moderate positive correlation with CIMT readings (r=0.493, p=0.000), while BMI(r=0.038, p=0.636), fasting blood glucose (r=0.038, p=0.646), triglyceride (r=0.179, p=0.029), and totalcholesterol (r=0.221, p=0.007) showed lesser correlations. Patients with hyperglycemia had higher CIMT[{Group-1, Normolycemia, FBG<5.5mmol/L = 0.667+0.137cm} {Group-2, Hyperglycemia, FBG>5.5mmol/L= 0.7180+0.147cm}(p=0.028)]. Mean CIMT values among subjects with hypertriglyceridemia andhypercholesterolemia were higher than patients with normal triglycerides and cholesterol [(triglyceride:p=0.040) (total cholesterol: p=0.055)].

Conclusion: The carotid intima medial layers were found to be thicker in subjects having higher bloodlevels of fasting blood glucose, triglycerides and total cholesterol.

Article Details

How to Cite
1.
Bokhari SAR, Khan SH, Hanif MS, Hassan M, Azam N. ASSOCIATION OF BLOOD LIPID AND GLUCOSE LEVELS WITH CAROTID INTIMA MEDIA THICKNESS. J Postgrad Med Inst [Internet]. 2013 Mar. 10 [cited 2024 May 30];27(2). Available from: https://www.jpmi.org.pk/index.php/jpmi/article/view/1350
Section
Original Article