Efficacy of high dose of magnesium sulphate for cardiac arrhythmias in patients of wheat pill poisoning

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Abdul Wahab Hassan
Muhammad Hussain Meo
Muhammad Najam Saqib
Nasreen Muhammad Saleem

Abstract

Objective: To study the prophylactic effects of High Dose Magnesium Sulphate on Cardiac Arrhythmias,Cardiogenic shock and associated mortality in Cases of Aluminum Phosphide Poisoning.

Methodology: Seventy One patients of wheat pill poisoning were randomly selected. Thirty seven weregiven high dose of Magnesium Sulphate (study group) and 34 were given low dose of magnesium sulphate(control group) through intravenous route along with other supportive measures. Patients were observedfor cardiac arrhythmias and mortality in both groups. Study end point was safe discharge from the hospitalor death.

Results: The mean age of the sample was 25.27+7.48 years. Frequency of cardiac arrhythmias was 40.54%(n=15) in study group versus 55.88% (n=19) in the control group. Average length of stay and frequency ofcardiogenic shock was slightly lower in the study group, i.e., 1.42+0.65 days while it was 1.78+1.38 daysfor the control group. Overall, mortality in both the groups was 66.20% (n=47), which remained almostequal in both groups or slightly favored study group with 64.86 % (n=24) in the study and 67.65% (n=23)in the control group.

Conclusion: High dose magnesium sulphate administration was found to be helpful for cardiac arrhythmiaand shock but mortality remained unchanged.

Article Details

How to Cite
1.
Hassan AW, Meo MH, Saqib MN, Saleem NM. Efficacy of high dose of magnesium sulphate for cardiac arrhythmias in patients of wheat pill poisoning. J Postgrad Med Inst [Internet]. 2013 Jun. 21 [cited 2022 May 23];27(3). Available from: https://www.jpmi.org.pk/index.php/jpmi/article/view/1402
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Original Article
Author Biographies

Abdul Wahab Hassan, Lahore General Hospital, Lahore

PG trainee and Medical Officer

Medical Unit III,

Lahore Genreal hospital.

Muhammad Hussain Meo, Lahore General Hospital, Defence national hospital, Lahore

Senior Registrar,

Med Unit III,

LGH, Lahore

Muhammad Najam Saqib, Lahore General Hospital, Lahore

Senior Registrar,

Lahore General Hospital, Lahore.

Nasreen Muhammad Saleem, Lahore General Hospital, Lahore

Senior Registrar,

Lahore General Hospital, Lahore.

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