CARBIMAZOLE INDUCED CHOLESTATIC HEPATITIS

Main Article Content

Hamza Ali Khan
Paul Peter
Giridhar Tarigopula
Praveen Partha

Abstract

Thyrotoxicosis is a common disorder especially in women. Most of the patientstolerate antithyroid medications very well with very few developing life threatening side effects. A 64 years old gentleman was diagnosed with hyperthyroidismsecondary to Grave's disease (autoimmune). He was treated withCarbimazole 20 mg daily. With in a month, he presented with acute cholestatichepatitis. The patient's symptoms and laboratory abnormalities resolved afterwithdrawing the offending drug and controlling his thyroid status first withbeta blocker and subsequently with propylethioracil. Since the mechanism of liver damage is different, antithyroid medications can be interchanged withoutincreasing the risk of further liver damage.

Article Details

How to Cite
1.
Khan HA, Peter P, Tarigopula G, Partha P. CARBIMAZOLE INDUCED CHOLESTATIC HEPATITIS. J Postgrad Med Inst [Internet]. 2014 Jan. 15 [cited 2022 May 26];28(1). Available from: https://www.jpmi.org.pk/index.php/jpmi/article/view/1511
Section
Case Report
Author Biographies

Hamza Ali Khan, *Specialist Registrar Department of Diabetes & Endocrinology Darlington Memorial Hospital Darlington, New Castle Upon Tyne and Wear, Kingston Park, North East England (United Kingdom) (Zip Code Number =NE32RD) @ST2 Department of Diabetes & Endocrinology Darlingon Memorial Hospital United Kingdom

*Specialist Registrar Department of Diabetes & Endocrinology Darlington Memorial Hospital Darlington, New Castle Upon Tyne and Wear, Kingston Park, North East England (United Kingdom)

(Zip Code Number =NE32RD)

@ST2 Department of Diabetes & Endocrinology Darlingon Memorial Hospital United Kingdom

Paul Peter, #Consultant Department of Diabetes and Endocrinology Darlington Memorial Hospital Darlington United Kingdom. Diabetes & Endocrinology Darlington Memorial Hospital Darlington, New Castle Upon Tyne and Wear, Kingston Park, North East England (United Kingdom) (Zip Code Number =NE32RD)

#Consultant Department of Diabetes and Endocrinology Darlington Memorial Hospital Darlington United Kingdom. Diabetes & Endocrinology Darlington Memorial Hospital Darlington, New Castle Upon Tyne and Wear, Kingston Park, North East England (United Kingdom)

(Zip Code Number =NE32RD)

Giridhar Tarigopula, #Consultant Department of Diabetes and Endocrinology Darlington Memorial Hospital Darlington United Kingdom. Diabetes & Endocrinology Darlington Memorial Hospital Darlington, New Castle Upon Tyne and Wear, Kingston Park, North East England (United Kingdom) (Zip Code Number =NE32RD)

#Consultant Department of Diabetes and Endocrinology Darlington Memorial Hospital Darlington United Kingdom. Diabetes & Endocrinology Darlington Memorial Hospital Darlington, New Castle Upon Tyne and Wear, Kingston Park, North East England (United Kingdom)

(Zip Code Number =NE32RD)

Praveen Partha, #Consultant Department of Diabetes and Endocrinology Darlington Memorial Hospital Darlington United Kingdom. Diabetes & Endocrinology Darlington Memorial Hospital Darlington, New Castle Upon Tyne and Wear, Kingston Park, North East England (United Kingdom) (Zip Code Number =NE32RD)

#Consultant Department of Diabetes and Endocrinology Darlington Memorial Hospital Darlington United Kingdom. Diabetes & Endocrinology Darlington Memorial Hospital Darlington, New Castle Upon Tyne and Wear, Kingston Park, North East England (United Kingdom)

(Zip Code Number =NE32RD)

Most read articles by the same author(s)

Similar Articles

You may also start an advanced similarity search for this article.