The improvement in the ABI index following 3 month treatment with cilostazol in patients with mild to moderate peripheral arterial disease

Main Article Content

Shams Suleman
M Abid Shah

Abstract

Objective: To study the effects of cilostazol in patients with mild to moder­ate peripheral arterial disease (PAD) using the improvement in ankle brachial pressure index (ABI).

Methodology: This hospital based interventionist study was a prospective, open labeled clinical trial. After the baseline data collection cilostazol was given to the group A, while the group B didn't receive cilostazol. The effect of intervention was noted at the timed study points at 4, 6 and 12 weeks .The antiplatelets were used in the group B as a control.

Results: The ABI improvement at the end of the study in the cilostazol treated group was marked compared with the control group. The group A had 65 males and 35 females, while the group B had 74 males and 26 females. The total ABI improved in the right and left lower limb with a P value of 0.001 each. The ABI results were better in the male, diabetic and hypertensive subsets of study as compared with female, obese and smoker.

Conclusion: Cilostazol significantly improves ABI in PAD. Its use in the indicat­ed population group should be encouraged to improve the management and prevent the complications.

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How to Cite
1.
Suleman S, Shah MA. The improvement in the ABI index following 3 month treatment with cilostazol in patients with mild to moderate peripheral arterial disease. J Postgrad Med Inst [Internet]. 2014 Jul. 25 [cited 2022 Jul. 7];28(3). Available from: https://www.jpmi.org.pk/index.php/jpmi/article/view/1534
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Original Article
Author Biographies

Shams Suleman, Assistant Professor , Khyber Girls Medical College

Pharmacology Dept,Khyber Girls Medical College

M Abid Shah, Khyber Medical College

Assistant Professor , Pharmacology Dept . Khyber Medical College Peshawar