Brain drain is the flow of skilled and qualified man power from a home country to host country leaving the former, socio-economically underdeveloped. The role of Pakistani medical diaspora in improving the health care system and socio-economic development of the country through brain circulation is discussed in this paper. Different secondary sources such as published research studies, government reports, newspapers and published interviews were consulted to gather information. The data collected was analyzed by using documentary and content analysis. Diaspora option can be used as a strategy to reverse and prevent the harmful effects of medical brain drain through brain gain and brain circulation. The government can play its vital role to facilitate the diaspora network between home and host countries. Diaspora networks should be mobilized to transfer knowledge, skills and ideas to their home country. However, diaspora networks are successful when home country is equipped with infrastructure, and with economic and political stability and strategic policies.