ROLE OF BRAIN NATRIURETIC PEPTIDE IN THE DIAGNOSIS AND MONITORING OF IRON DEFICIENT CHRONIC HEART FAILURE PATIENTS

Main Article Content

Nadia Kashif
Mohammad Tariq Masood
Hidayat Ullah
Adnan Gul
Zahid Aslam Awan
Mohammad Hafizullah
Jawad Ahmed
Abid Sohail Taj

Abstract

Objectives: To determine the efficacy of intravenous iron administration in
iron deficient chronic heart failure patients and to determine the role of brain
natreuretic peptide (BNP) in the diagnosis and monitoring of chronic heart
failure patients.
Methodology: The current study was a prospective analytical study. A total
of 96 patients with symptomatic chronic heart failure (CHF) were selected
through convenient sampling method. These were divided in to several
groups based upon findings of echocardiography, 06 minutes' walk test and
serum BNP. It was found that 38 patients were iron deficient. Intravenous (I/V)
iron sucrose was administered to iron deficient patients weekly for 6 weeks
followed by reassessment; the compliance rate was 87%.
Results: Patients managed with I/V therapy showed significant improvement
in all the clinical and biochemical parameters used in the study. New York
Heart Association class shift was seen in 76% of patients.
Conclusions: iron deficient induced CHF is common in our population. Parenteral
iron administration (iron sucrose) is an effective modality for managing
such patients. Serial BNP levels can be used to monitor the response to IV
iron.

Article Details

How to Cite
1.
Kashif N, Masood MT, Ullah H, Gul A, Awan ZA, Hafizullah M, Ahmed J, Taj AS. ROLE OF BRAIN NATRIURETIC PEPTIDE IN THE DIAGNOSIS AND MONITORING OF IRON DEFICIENT CHRONIC HEART FAILURE PATIENTS. J Postgrad Med Inst [Internet]. 2016 Nov. 26 [cited 2022 Jul. 7];30(4). Available from: https://www.jpmi.org.pk/index.php/jpmi/article/view/1937
Section
Original Article
Author Biographies

Nadia Kashif, Khyber Medical University

Haematology. M.Phil Students

Mohammad Tariq Masood, Khyber Medical University

Hematology

Hidayat Ullah, Lady Reading Hospital

Cardiology

Adnan Gul, Lady Reading Hospital

Cardiology

Zahid Aslam Awan, Hayatabad Medical Complex

Cardiology

Mohammad Hafizullah, Khyber Medical University

Cardiology

Jawad Ahmed, Khyber Medical University

Microbiology

Abid Sohail Taj, Institute of Basic Medical Sciences

Hematology

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