Mucosal Protective Mechanisms
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Abstract
Cytoprotection is the ability of agents to inhabit injury to the gastro-duodenal mucosa and promote healing of ulcerations without inhibiting acid secretion or neutralizing intra-lumenal acidity.
Cytoprotective agents: Prostaglandins (PGS), Essential fatty acids (EFA) and Sucralfate ___
Do not prevent initial disruption of the surface epithelium after exposure to necrotizing agents but
Prevent damage to the mucosal proliferative zone enabling prompt restitution of the mucosal surface.
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