@article{Akhtar_Qazi_Khan_2011, title={PROSTAGLANDIN F2 ALPHA: AN EFFECTIVE ALTERNATE TO SURGICAL CONTROL OF POSTPARTUM HEMORRHAGE IN UTERINE ATONY}, volume={24}, url={https://www.jpmi.org.pk/index.php/jpmi/article/view/1003}, abstractNote={<strong><em><span style="font-family: TimesNewRomanPSMT,BoldItalic; font-size: x-small;"><strong><span style="font-family: TimesNewRomanPSMT,BoldItalic; font-size: x-small;"><strong><span style="font-family: TimesNewRomanPSMT,BoldItalic; font-size: x-small;"><p>Objectives:</p></span></strong></span></strong></span><p> </p></em></strong><span style="font-family: TimesNewRomanPSMT,Italic; font-size: x-small;"><em><p><span style="font-family: TimesNewRomanPSMT,Italic; font-size: x-small;">To find out the use of Prostaglandin F2 alpha to avoid the surgical control of primary</span><strong><em><span style="font-family: TimesNewRomanPSMT,BoldItalic; font-size: x-small;"><strong><span style="font-family: TimesNewRomanPSMT,BoldItalic; font-size: x-small;"><strong><span style="font-family: TimesNewRomanPSMT,BoldItalic; font-size: x-small;"><p>Material and Methods:</p></span></strong></span></strong></span><p> </p></em></strong><span style="font-family: TimesNewRomanPSMT,Italic; font-size: x-small;"><em><p><span style="font-family: TimesNewRomanPSMT,Italic; font-size: x-small;">This was a Quasi-Experimental study carried out in obstetrics & gynecology unit<p>B of Khyber Teaching Hospital Peshawar from 1st July 2003 – 30th June 2004. 50 patients having primary</p><p>post partum hemorrhage due to uterine atony not responding to conventional oxytocics were given systemic</p><p>and local prostaglandin F2 alpha. Vital signs, estimated blood loss and effect on uterine muscular tone</p><p>were noted before & after prostaglandin F2 alpha. Surgical interventions were used in patients with</p><p>continuous profuse vaginal bleeding despite maximum dose of prostaglandin F2 alpha and/ or</p></span></p><p>hemodynamic instability of the patients. A semi-structured proforma was used to collect the data.</p><strong><em><span style="font-family: TimesNewRomanPSMT,BoldItalic; font-size: x-small;"><strong><span style="font-family: TimesNewRomanPSMT,BoldItalic; font-size: x-small;"><strong><span style="font-family: TimesNewRomanPSMT,BoldItalic; font-size: x-small;"><p>Results:</p></span></strong></span></strong></span><p> </p></em></strong><span style="font-family: TimesNewRomanPSMT,Italic; font-size: x-small;"><em><p><span style="font-family: TimesNewRomanPSMT,Italic; font-size: x-small;">A total of 44 (88%) patients responded well to the drug. Estimated blood loss before<p>prostaglandin F2 alpha was 1000 - 4000ml with mean of 2250.00 + 686.98ml as compared to 416.00 +</p><p>294.41ml after prostaglandin F2 alpha was used. Side effects of the drug were mostly self limiting and</p></span></p><p>required symptomatic treatment. No maternal death was recorded.</p><strong><em><span style="font-family: TimesNewRomanPSMT,BoldItalic; font-size: x-small;"><strong><span style="font-family: TimesNewRomanPSMT,BoldItalic; font-size: x-small;"><strong><span style="font-family: TimesNewRomanPSMT,BoldItalic; font-size: x-small;"><p>Conclusion:</p></span></strong></span></strong></span><p> </p></em></strong><span style="font-family: TimesNewRomanPSMT,Italic; font-size: x-small;"><em><p><span style="font-family: TimesNewRomanPSMT,Italic; font-size: x-small;">Prostaglandin F2 alpha is an effective drug to control Primary post partum hemorrhage due<p>to uterine atony and avoids surgical interventions in most of the patients. Side effects are minimum, most</p></span></p><p>of which are self limiting.</p></em></span></em></span></em></span></p><p>postpartum hemorrhage due to uterine atony and the adverse effects associated with prostaglandin F2</p><p>alpha.</p></em></span>}, number={1}, journal={Journal of Postgraduate Medical Institute}, author={Akhtar, Zubaida and Qazi, Qudsia and Khan, Imran}, year={2011}, month={Oct.} }