@article{Paracha_Khurshid_Pal_Ali_2011, title={COMPARISON OF TREATMENT WITH TACROLIMUS 0.03% AND SUPEROXIDE DISMUTASE AND CATALASE IN VITILIGO}, volume={24}, url={https://www.jpmi.org.pk/index.php/jpmi/article/view/1224}, abstractNote={Objective: To compare the efficacy and safety of topical tacrolimus 0.03% with superoxide dismutase and<br />catalase in vitiligo.<br />Material and methods: This hospital based quasi-experimental study was carried out in out patients<br />department of Dermatology Unit-II, Mayo Hospital Lahore in year 2006-2007. Patients were selected by<br />non-probability purposive sampling method after obtaining an informed consent. Both sexes (above 5<br />years) were included with head and neck vitiligo. They were randomly divided into 2 groups; group 1:<br />superoxide dismutase and catalase; group 2: tacrolimus by using random number table.<br />Results: There were 34(56.7%) females and 26(43.3%) males. Age of the patients ranged from 5 to 60<br />years with the mean age of 20.52+14.34 years. Overall 31(62%) patients showed repigmentation of varied<br />grades. Repigmentation was shown by 14(46.6%) patients in superoxide dismutase & catalase group and<br />17(56.6%) patients in tacrolimus group.<br />Conclusion: Topical superoxide dismutase & catalase and tacrolimus are effective treatment modalities in<br />patients with vitiligo. There is no significant difference regarding efficacy and safety between both forms of<br />treatment.}, number={2}, journal={Journal of Postgraduate Medical Institute}, author={Paracha, Mohammad Majid and Khurshid, Khawar and Pal, Sabrina Suhail and Ali, Zafar}, year={2011}, month={Oct.} }