@article{Mohammad_2016, title={IS ONCOLYTIC VIROTHERAPY A VIABLE PLATFORM FOR GLIOMA TREATMENT?}, volume={30}, url={https://www.jpmi.org.pk/index.php/jpmi/article/view/1847}, abstractNote={<div><p>Gliomas are devastating cancers of the nervous system with poor prognosis. <br />Their aggressiveness produces a mortality rate rarely seen with other malig-nant tumours and the lack of effective treatment has left very few options. On-colytic viruses, with their long history of experimentation, have been deemed <br />to be a key player in the future treatment of gliomas. This review will focus <br />on the two main contenders, adenovirus and herpes simplex virus, for glioma <br />treatment and discuss how far the field has come since its conception. The <br />concept of each vector and the rationales behind their use will be contrasted <br />before discussing the future of the field. Data was located by accessing the <br />MEDLINE database using the PubMed search system. Data was selected on <br />the basis of the insight its information provided as well as on the dependabil -ity of the experimental method used.</p></div>}, number={1}, journal={Journal of Postgraduate Medical Institute}, author={Mohammad, Fahad}, year={2016}, month={Feb.} }