TY - JOUR AU - Rauf, Muhammad Abdur AU - Aman, Wahaj AU - Shah, Syed Tahir AU - Khan, Noman AU - Khan, Sher Bahadar AU - Khan, Imtiaz AU - Mahmood, Nida AU - Hafizullah, Mohammad PY - 2012/06/29 Y2 - 2024/03/28 TI - EFFECT OF INTERVENTION ON THE CONTROL OF RISK FACTORS IN CORONARY ARTERY DISEASE PATIENTS JF - Journal of Postgraduate Medical Institute JA - J Postgrad Med Inst VL - 26 IS - 3 SE - Original Article DO - UR - https://www.jpmi.org.pk/index.php/jpmi/article/view/1297 SP - AB - Objective: To assess the effect of optimal medical therapy on the control of risk factors in coronary artery<br />disease (CAD) patients with or with-out intervention.<br />Methodology: It was a cross sectional comparative study carried out at Lady Reading Hospital, Peshawar<br />January to December 2010. Subjects were divided into two groups based on percutaneous coronary<br />intervention and optimal medical therapy. Study variables were smoking, physical activity, dyslipidemia,<br />diabetes, hypertension and obesity. Informed written consent was taken from all the study participants.<br />Data was recorded on a preformed Questionnaire and analyzed with SPSS version 16. P-value of 0.05 was<br />taken as significant.<br />Results: A total of 315 patients were studied. Baseline characteristic were similar between groups.<br />Smoking was decreased significantly in(PCI group) as compared to (OMT group) (p=0.027). Physical<br />activity goal ≥ 150 min/ week were achieved more in (PCI group) compared to (OMT group)(p=0.019).<br />Goals set for Serum cholesterol, HbA1c%, serum LDL, Systolic blood pressure and Diastolic blood<br />pressure have significantly achieved in (PCI group) as compared to (OMT group) with p- valves of<br />(0.018,0.027,0.023,0.033 and 0.017) respectively. While goals set for Triglycerides, serum HDL and BMI<br />have no significant difference between the two groups with p-valves of (0.223, 0.089 and 0.164<br />respectively).<br />Conclusion: Patients who underwent intervention and remained on optimal medical therapy were more<br />adherent to regular exercise and good compliance which lead to better risk factors control for coronary<br />artery disease as compared to patients who remained on optimal medical therapy alone. ER -