Main Article Content
This study was done to determine the sensitivity and resistance pattern to the most commonantibiotics in use.
The data for this retrospective study was obtained and analysed from October 2010 toOctober 2011 in Lady Reading Hospital, Peshawar. Purposive sampling and univariate analysis was done.2058 samples were cultured for sensitivity using Kirby Bauer's Diffusion technique and in a period of oneyear, growth of Staphylococcus aureus was obtained in 723 samples. These 723 growths were obtainedfrom clinical isolates of pus (699), blood (16) and urine (8). Fourteen drugs from five different classes ofantibiotics were tested for sensitivity against Staphylococcus aureus.
ResultsMost of the growth was obtained from pus (96.7%). Resistance was high to all groups ofantibiotics except glycopeptides. There was no case of Vancomycin Resistant Staphylococcus aureus(VRSA). Out of 723 samples, 228 (31.5%) were Methicillin Resistant Staphylococcus aureus (MRSA). Theresistance to a representative antibiotic of each group is as follows: Ciprofloxacin (Fluoroquinolone)51.7%, Cephradine (Cephalosporin) 46.2%, Amoxicillin+Clavulanic Acid (Penicillin group) 45.6%,Imipenem+Cilastatin Sodium (Carbapenem) 42.0% and Teicoplanin (Glycopeptide) 19.8%.
Resistance of Staphylococcus aureus to Teicoplanin and most of the antibiotics is high andstrict guidelines are required to control unnecessary prescriptions and over the counter sale of antibiotics.
Work published in JPMI is licensed under a
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.