HEART FAILURE CLINICAL OUTCOMES IN HYPONATREMIC VERSUS NORMONATREMIC PATIENTS

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Farooq Ahmad
Muhammad Adil
Ikram Ullah
Salman Ahmad
Yasir Hayat
Mohammad Hafizullah

Abstract

Objective: To compare the outcome in heart failure patients between normonatremic and hyponatremic cases in the short term.

Methodology: A cross-sectional study focusing on descriptive statistics atthe Department of Cardiology, Lady Reading Hospital Peshawar was performedfrom 9th August 2011, till 29th April, 2012. Both male and femalepatients aged 14 years and above admitted diagnosed with heart failure wereenrolled and data observed. Those having serum sodium of ≤135mmol/Lwere defined as hyponatremic. All the patients were managed according toguidelines. All patients were followed during their hospital stay. Patients whosurvived were discharged on standard HF medications and followed till theend of third month for 3 month mortality and re-admissions for heart failure.

Results: Total study population was 241. Mean age was 59.2 ± 14.9 (18-100) years. Female patients were 51% (123). Mean serum sodium was136±5.1mmol/L (116-151). Hyponatremia was present in 35.3% (85) patients.Overall three month follow up mortality was 14.7%, while it was significantlyhigher in hyponatremic group 22.7% compared to normonatremic patients10.7% (P=0.02). Being followed for a period of 3 months 25% patients werereadmitted to hospital with heart failure decompensation. Hyponatremicgroup had readmission rate of 26.7% compared with 24% in normonatremicpatients (p=0.74).

Conclusions: Hyponatremia in patients diagnosed with heart failure possessa significant over all risk to a higher mortality as compared to those that arenormonatremic. Re-admissions for heart failure are equally common in hyponatremic and normonatremic patients.

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How to Cite
1.
Ahmad F, Adil M, Ullah I, Ahmad S, Hayat Y, Hafizullah M. HEART FAILURE CLINICAL OUTCOMES IN HYPONATREMIC VERSUS NORMONATREMIC PATIENTS. J Postgrad Med Inst [Internet]. 2015 May 20 [cited 2022 Jan. 22];29(2). Available from: https://www.jpmi.org.pk/index.php/jpmi/article/view/1658
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Original Article
Author Biographies

Muhammad Adil

Senior Registrar cardiology, PGMI LRH peshawar

Salman Ahmad, Cardiology Department, Khalifa Gulnawaz Hospital, Bannu

Medical officer cardiology

Mohammad Hafizullah, Cardiology Department, PGMI, Lady Reading Hospital, Peshawar

Professor and head cardiology department pgmi lrh

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