Comparative evaluation of conventional medical treatment alone versus conventional medical treatment with amniotic membrane transplantation in infective corneal ulcer

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Muhammad Naeem
Mushtaq Ahmad
Hina Mehwish Khan
Mohammad Naeem Khan

Abstract

Objective: To compare the effect of amniotic membrane transplantationalong with conventional therapy and the conventional therapy alone for thetreatment of infective corneal ulcer.Methodology: This study was conducted at Ophthalmology Department, HayatabadMedical Complex Peshawar. The duration of study was 6 months, i.e.,from April 2010 to October 2010, in which a total of 68 patients were includedusing WHO software for sample size determination. They were divided intotwo equal groups of 34 each. Non probability purposive sampling techniquewas used.Results: In this study, mean age was 50±0.24 years. Forty six (67.6%) patientsweremale while 32.4% (n=22) patients were female. Conventional MedicalTreatment alone was effective in 87% (n=30) cases while Conventional MedicalTreatment with Amniotic Membrane was effective in 96% (n=33) caseswith a p-value of 0.03.Conclusion: This study showed encouraging results of amniotic membranetransplantation along with conventional treatment in corneal ulcer in improvingboth symptoms and signs.

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Naeem M, Ahmad M, Khan HM, Khan MN. Comparative evaluation of conventional medical treatment alone versus conventional medical treatment with amniotic membrane transplantation in infective corneal ulcer. J Postgrad Med Inst [Internet]. 2014 Apr. 17 [cited 2022 May 28];28(2). Available from: https://www.jpmi.org.pk/index.php/jpmi/article/view/1521
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