Comparative evaluation of conventional medical treatment alone versus conventional medical treatment with amniotic membrane transplantation in infective corneal ulcer
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Objective: To compare the effect of amniotic membrane transplantationalong with conventional therapy and the conventional therapy alone for thetreatment of infective corneal ulcer.Methodology: This study was conducted at Ophthalmology Department, HayatabadMedical Complex Peshawar. The duration of study was 6 months, i.e.,from April 2010 to October 2010, in which a total of 68 patients were includedusing WHO software for sample size determination. They were divided intotwo equal groups of 34 each. Non probability purposive sampling techniquewas used.Results: In this study, mean age was 50±0.24 years. Forty six (67.6%) patientsweremale while 32.4% (n=22) patients were female. Conventional MedicalTreatment alone was effective in 87% (n=30) cases while Conventional MedicalTreatment with Amniotic Membrane was effective in 96% (n=33) caseswith a p-value of 0.03.Conclusion: This study showed encouraging results of amniotic membranetransplantation along with conventional treatment in corneal ulcer in improvingboth symptoms and signs.
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