CORRELATION BETWEEN GLYCOSYLATED HEMOGLOBIN AND PLATELET ACTIVITY AMONG PATIENTS WITH TYPE 2 DIABETES MELLITUS

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Iftikhar Muhammad
Iqbal Haider
Aliena Badshah
Zeeshan Murtaza

Abstract

Objective: To determine the correlation between glycosylated hemoglobinlevel and platelet activity among patients with type 2 diabestes mellitus(T2DM).

Methodology: This study was conducted in the Department of Medicine,Khyber Teaching Hospital, Peshawar from January to June 2012. Through aComparative Cross Sectional Study Design, a total of 80 patients with T2DMwere selected from Medical Wards and OPDs and were grouped into thosewith glycated hemoglobin (HbA1c) levels < 7% (Group A, n=33) and thosewith HbA1c ≥ 7% (Group B, n=47 patients). Both the groups were comparedwith regards to MPV and HbA1c.

Results: The mean age of patients was 47.41 ± 6.74 years. In group A there were 45.5% (15) males and 54.5% (18) females. In group B there were 48.9%(23) males and 51.1% (24) female patients. MPV was significantly higher in group B as compared to group A (9.21±0.76 fl vs. 8.29±0.46 fl; P < 0.001).Among the group B patients, a positive statistical Pearson's correlation was seen between MPV and HbA1c levels (r = 0.589; p < 0.001). However, no statistical correlation was seen between MPV and the duration of DM and BMI.

Conclusions: There is a significant association between poor glycemic controland increased platelet activity in patients with uncontrolled T2DM.

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How to Cite
1.
Muhammad I, Haider I, Badshah A, Murtaza Z. CORRELATION BETWEEN GLYCOSYLATED HEMOGLOBIN AND PLATELET ACTIVITY AMONG PATIENTS WITH TYPE 2 DIABETES MELLITUS. J Postgrad Med Inst [Internet]. 2015 May 20 [cited 2022 May 21];29(2). Available from: https://www.jpmi.org.pk/index.php/jpmi/article/view/1657
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Original Article
Author Biographies

Iftikhar Muhammad, Department of Medicine, Khyber Teaching Hospital Peshawar

Training Medical Officer, Department of Medicine , Khyber Teaching Hospital Peshawar

Iqbal Haider, Department of Medicine, Khyber Teaching Hospital Peshawar

Senior Registrar, Department of Medicine , Khyber Teaching Hospital Peshawar

Aliena Badshah, Department of Medicine, Khyber Teacing Hospital Peshawar

Training Medical Officer, Khyber Teaching Hospital Peshawar

Zeeshan Murtaza, Department of Medicine, KTH Peshawar

Training Medical Officer, Department of Medicine, KTH Peshawar

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