MANAGEMENT OF FIRST TRIMESTER MISCARRIAGE BY 800-μG VAGINAL MISOPROSTOL COMPARED WITH EXPECTANT MANAGEMENT
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Published:
May 12, 2017
Keywords:
First trimester miscarriage, Misoprostol, Expectant management
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Abstract
Objective: To compare the safety and effectiveness of expectant management
with medical management by misoprostol in cases of first trimester miscarriage.
Methodology: This case-control study was conducted in the Department of
Obstetrics and Gynecology, Liaquat University Hospital, Hyderabad (Sindh) Pakistan,
from December 2010 to November 2012 (two years). From 124 women,
62 were managed by up to two doses of 800-μg misoprostol intra-vaginally
and 62 expectantly. If products of conception were not completely expelled till
7th day then manual vacuum aspiration or dilatation and curettage was performed.
Reports of complications were sought up to 8 weeks.
Results: There was 83.87% success rate in misoprostol group and 48.39% in
expectant management group (P<0.001). No statistically significant difference
in side-effects or complications was observed. Patient satisfaction rate was significantly
higher in misoprostol group (P<0.01).
Conclusion: Vaginal misoprostol is almost as safe as expectant management as
well as significantly more efficient and satisfactory for the management of first
trimester miscarriages.
with medical management by misoprostol in cases of first trimester miscarriage.
Methodology: This case-control study was conducted in the Department of
Obstetrics and Gynecology, Liaquat University Hospital, Hyderabad (Sindh) Pakistan,
from December 2010 to November 2012 (two years). From 124 women,
62 were managed by up to two doses of 800-μg misoprostol intra-vaginally
and 62 expectantly. If products of conception were not completely expelled till
7th day then manual vacuum aspiration or dilatation and curettage was performed.
Reports of complications were sought up to 8 weeks.
Results: There was 83.87% success rate in misoprostol group and 48.39% in
expectant management group (P<0.001). No statistically significant difference
in side-effects or complications was observed. Patient satisfaction rate was significantly
higher in misoprostol group (P<0.01).
Conclusion: Vaginal misoprostol is almost as safe as expectant management as
well as significantly more efficient and satisfactory for the management of first
trimester miscarriages.
Article Details
How to Cite
1.
Dars S, Akhter N, Malik S. MANAGEMENT OF FIRST TRIMESTER MISCARRIAGE BY 800-μG VAGINAL MISOPROSTOL COMPARED WITH EXPECTANT MANAGEMENT. J Postgrad Med Inst [Internet]. 2017 May 12 [cited 2024 Apr. 18];31(2). Available from: https://www.jpmi.org.pk/index.php/jpmi/article/view/1987
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