CORRELATION OF SUBCLINICAL THYROID DYSFUNCTION WITH DYSLIPIDEMIA
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Published:
May 12, 2017
Keywords:
Sub-clinical thyroid dysfunction, Sub-clinical hypothyroidism, Subclinical hyperthyroidism, Dyslipidemia, Overt hyperthyroidism
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Abstract
Objective: To determine the relationship between sub-clinical thyroid
dysfunction (STD) and dyslipidemia.
Methodology: This cross sectional study was conducted in Pakistan Health Research
Centre (PHRC), Khyber Medical College and Khyber Medical University,
Hayatabad Peshawar, Pakistan in the year 2012-2013. Thirty patients of both
genders and between 10-70 years of age, residing in Peshawar were studied.
Lipid profiles were assessed for relationship with sub-clinical hypothyroidism
(SCH-I) and sub-clinical hyperthyroidisms (SCH-II).
Results: Total cholesterol (TC) was 194.67 ±34.81 in (SCH-I) and 151.29 ±35.22
in (SCH-II); low density lipoprotein cholesterol (LDL-C) was 146.56 ±47.6 in
(SCH-I) and 89.48 ±27.15 in (SCH-II); triglycerides (TG) were 91.89 ±33.62 in
(SCH-I) and 125.62 ±68.98 in (SCH-II). Serum TC and LDL-C levels were significantly
high in SCH-I (p values 0.033 & 0.029 respectively). Serum TC, LDL-C,
VLDL-C and TG levels were negatively correlated with STD (r values -0.601,
-0.533, -0.401 & -0.401 respectively).
Conclusions: Serum TC and LDL-C levels were high in SCH-I. Lipid profile was
non-significant in SCH-II patients. Serum TC, LDL-C, VLDL-C and TG were negatively
correlated with STD.
dysfunction (STD) and dyslipidemia.
Methodology: This cross sectional study was conducted in Pakistan Health Research
Centre (PHRC), Khyber Medical College and Khyber Medical University,
Hayatabad Peshawar, Pakistan in the year 2012-2013. Thirty patients of both
genders and between 10-70 years of age, residing in Peshawar were studied.
Lipid profiles were assessed for relationship with sub-clinical hypothyroidism
(SCH-I) and sub-clinical hyperthyroidisms (SCH-II).
Results: Total cholesterol (TC) was 194.67 ±34.81 in (SCH-I) and 151.29 ±35.22
in (SCH-II); low density lipoprotein cholesterol (LDL-C) was 146.56 ±47.6 in
(SCH-I) and 89.48 ±27.15 in (SCH-II); triglycerides (TG) were 91.89 ±33.62 in
(SCH-I) and 125.62 ±68.98 in (SCH-II). Serum TC and LDL-C levels were significantly
high in SCH-I (p values 0.033 & 0.029 respectively). Serum TC, LDL-C,
VLDL-C and TG levels were negatively correlated with STD (r values -0.601,
-0.533, -0.401 & -0.401 respectively).
Conclusions: Serum TC and LDL-C levels were high in SCH-I. Lipid profile was
non-significant in SCH-II patients. Serum TC, LDL-C, VLDL-C and TG were negatively
correlated with STD.
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How to Cite
1.
Attaullah S, Haq BS. CORRELATION OF SUBCLINICAL THYROID DYSFUNCTION WITH DYSLIPIDEMIA. J Postgrad Med Inst [Internet]. 2017 May 12 [cited 2024 Apr. 23];31(2). Available from: https://www.jpmi.org.pk/index.php/jpmi/article/view/2003
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