THE CORRELATION BETWEEN PLASMA D-DIMER LEVEL AND LESION VOLUME IN ACUTE ISCHEMIC STROKE

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Amina Noor
Hassan Mustafa
Syed Affan Ali
Sumera kazmi
Nasma Noor
Saqib Malik

Abstract

Objective: To find out correlation between serum D-dimer and lesion volume in acute ischemic stroke. Methodology: This cross-sectional study was conducted in Ayub Teaching Hospital, Abbottabad from April 2018 to December 2018. A total of 83 patients with ischemic stroke were enrolled in this study using non-probability consecutive sampling. Diagnosis was made on history, examination and computerized tomography (CT) brain findings. A pre-designed proforma was used to collect data, which was analyzed using SPSS version 20. Descriptive and inferential statistics were applied where needed. Results: Out of 83 patients, the mean age was 52.78 ± 10.37 years with range from 35 to 65 years. In total, 64 (77.11%) were males. Infarct volume on CT ranged from 18.00 to 192.00 cc with mean of 74.10 ± 35.02 cc. Plasma D-dimer level ranged from 10 to 200 µg/l with mean of 80.23 ± 54.65. Gender stratification of age, infarct volume and plasma D-dimer in male revealed means of 53.41 ± 10.30, 74.01 ± 34.98, and 82.20 ± 55.64 respectively, while in females means were recorded as 50.68 ± 10.58, 74.42 ± 36.11, and 73.58 ± 52.08 respectively. The correlation statistics, between infarct volume and plasma D-dimer level revealed significant positive correlation (r=0.537; p=<0.001). Correlation was further stratified based on gender and a significatly positively corelation coefficient was found. Conclusion: Significant positive correlation was found between plasma D-dimer and lesion volume in acute ischemic stroke. 

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How to Cite
1.
Noor A, Mustafa H, Ali SA, kazmi S, Noor N, Malik S. THE CORRELATION BETWEEN PLASMA D-DIMER LEVEL AND LESION VOLUME IN ACUTE ISCHEMIC STROKE. J Postgrad Med Inst [Internet]. 2020 Oct. 22 [cited 2024 Oct. 3];34(2). Available from: https://www.jpmi.org.pk/index.php/jpmi/article/view/2667
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Original Article
Author Biographies

Amina Noor, Abbottabad International Medical College

Senior registrar, Medicine Department

 

Hassan Mustafa, Ayub Teaching Hospital

Medical Officer,

Medical C ward.

Syed Affan Ali, Abbottabad International Medical College

Assistant Professor,

Department of medicine

Sumera kazmi, Abbottabad International Medical College

Associate professor,

Department of medicine

Nasma Noor, Hayatabad Medical Complex, Peshawar

Training medical officer,

Dermatology

Saqib Malik, Ayub Teaching Hospital, Abbottabad

Associate professor,

Department of medicine

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