ROLE OF TOPICAL NEPAFENAC IN PREVENTING INCREASE IN MACULAR THICKNESS AFTER PHACOEMULSIFICATION

Main Article Content

Wali Ullah
Muhammad Irfan
Shahid Abdur Rauf Khan
Adnan Ghalib
Zia Uddin Khalil

Abstract

Objective: To compare mean increase in macular thickness in patients using topical Nepafenac and standard treatment with standard treatment alone, after phacoemulsifation.

Methodology: This was a comparative cross sectional study which involved 84 patients operated for age related cataract. Pre-operative ocular coherence tomography was performed to document the central macular thickness and patients were randomly allocated to 2 groups. Group A received topical Nepafenac 0.1% in addition to the standard post-operative topical medication. Group B received only standard regimen of topical medications including antibiotics and steroids. Phacoemulsification was performed in both groups. Post-operative OCT was done to measure central macular thickness after 2 months of surgery. Mean increase in central macular thickness was compared between the two groups.

Results: Out of 84 patients, males were 45 (53.57%) and females were 39 (46.42%). Male to female ratio was 1: 1.15.  Average age was 58.65 years + 6.01 SD. The mean pre-operative macular thickness was 234.4 um + 1.72 SD while the mean post-operative macular thickness was 240.07 um + 11.43 SD. The mean increase in macular thickness was 6.85um + 4.69SD. Group A (Nepafenac group) showed significantly lesser increase in macular thickness after cataract surgery as compared to Group B (Non- Nepafenac group).

Conclusion: Topical Nepafenac is associated with less mean increase in macular thickness after cataract surgery. It has a prophylactic role and reduces the occurrence of post-operative macular edema.

 

 

Article Details

How to Cite
1.
Ullah W, Irfan M, Khan SAR, Ghalib A, Khalil ZU. ROLE OF TOPICAL NEPAFENAC IN PREVENTING INCREASE IN MACULAR THICKNESS AFTER PHACOEMULSIFICATION. J Postgrad Med Inst [Internet]. 2021 Mar. 20 [cited 2024 Mar. 29];34(4). Available from: https://www.jpmi.org.pk/index.php/jpmi/article/view/2739
Section
Original Article

Most read articles by the same author(s)

<< < 1 2 3 4 > >>