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To find out the sensitivity and specificity of dobutamine stress echocardiography in comparison
This Cross-Sectional study was conducted at cardiology department, Lady Reading Hospital
Peshawar, from January to December 2007. Data was collected by non probability purposive sampling
technique. Study patients underwent both dobutamine stress echo and coronary angiography, after taking
an informed consent. Dobutamine stress echo was performed according to standard protocol.
Total of 50 patients, whose mean age was 51.6+/-9.7, were studied. Men were 35 (70%) and
women were 15 (30%). Dobutamine was infused (10 to 40 micrograms/kg/min) in 3 minutes intervals. The
inducible ischemia was detected in total 33(66%) patients. Seven patients (14%) had only resting wall
motion abnormalities with no change by dobutamine stress. These patients were also taken as positive for
ischemia. Coronary angiography showed 43/50 (86%) patients had > 50% stenosis in at least one
coronary artery. Compared with coronary angiography, the sensitivity, specificity, positive and negative
predictive values and accuracy of dobutamine stress echo for detection of coronary artery disease were
91%, 86%, 97%, 60%and 90% respectively. The sensitivities for SVD, DVD and TVD were 76%, 89% and
Dobutamine stress echo is a sensitive and specific method in non invasive diagnosis of
suspected CAD. It is highly sensitive for multivessel disease as compared to single vessel disease.
to the angiographic findings.
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