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Methodology: This study was carried out on pregnant women referring for
delivery in Hamadan province in west of Iran. We retrospectively evaluated
medical records of all referring subjects to medical centers in Hamadan prov-ince between 1997 and 2006. All pregnant women referred to 11 referral hos -pitals as well as obstetric care facility centers in the province were studied.
We recorded all cases with hydatidiform mole. Data Processing and statistical
analysis were performed using SPSS version 16.0.
Results: The incidence of hydatidiform mole in Hamadan province estimat -ed 3.34 per 1000 pregnancies Between 1997 and 2006. It means 1 per 298.2
pregnancies had hydatidiform mole. The incidence rate of hydatidiform mole
was considerably higher compared to reported from Japan, Turkey, Europe,
USA, UK, China, Malaysia, whereas was lower than reported from Indonesia
and India. The risk of recurrence rate of mole was higher than that reported in
the UK, but lower than that shown in South Africa.
Conclusion: The incidence of hydatidiform mole in Hamadan province of Iran
seems to be high. Therefore early and rapid diagnosis of gestational tropho -blastic diseases in this region is strongly recommended.
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